The kidneys have three basic functions

on December 02, 2022
The kidneys have three basic functions:

1. Generate urine and excrete metabolites:

The body produces a variety of waste products in the process of metabolism, most of which are filtered through glomerular blood, secreted by renal tubules, and excreted with urine.

2. Holding body fluid balance and acid-base balance in the body:

The kidneys pass through the glomerular filtration, reabsorption and secretion of the renal tubules, excrete excess water in the body, regulate the acid-base balance, and maintain the stability of the internal environment.

3. Endocrine function:

(1) Secretion of renin, prostaglandins, kinins. Blood pressure is regulated by renin-angiotensin-aldosterone system and kalin-bradykinin-prostaglandin system.

(2) Erythropoietin. Stimulates bone marrow hematopoiesis.

(3) Active VitD3. Regulates calcium and phosphorus metabolism.

(4) Many endocrine hormone degradation sites - such as insulin, gastrointestinal hormones, etc. When renal insufficiency these hormones T1/2 are significantly prolonged, causing metabolic disorders.

(5) Target organs of extrarenal hormones. Such as parathyroid hormone, calcitonin, etc. It can affect and regulate kidney function.

It can be seen that the kidneys play an important role in maintaining the stability of the internal environment.

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